Business

Pharmaceutical giant CVS closes 271 stores in the U.S.: these are the known affected stores

CVS announced that it will be “strategically” closing 271 locations in order to “better meet consumers’ health, wellness and pharmacy care needs.”

Greg Heilman

Update: May 30th, 2025 05:46 EDT

CVS plans to close more stores in 2025 as part of its ongoing restructuring efforts to “streamline and simplify” operations company-wide. The drug store chain told Newsweek that it is shuttering 271 locations not because of industry pressures but to “enable the company to better meet customers’ needs.”

“Store closure decisions are based on several factors, including population shifts, consumer buying patterns, store and pharmacy density, pharmacy care access, and community health needs,” a company spokesperson said in a statement. “We’re focused on ensuring we have the right kinds of stores and the right number of stores in the right locations.”

Where CVS will be closing stores

The drug store chain did not provide Newsweek with a list of stores that will be closing but The Krazy Coupon Lady, a media company that helps shoppers “unapologetically maximize their money,” published a list of 34 locations CVS has either already closed or that are scheduled to shut their doors in 2025 according to local media reports.

CVS store closures in 2025:

Alabama

2901 Morgan Rd., Bessemer
3303 Clairmont Ave., Birmingham

California

499 Haight St., San Francisco
1701 K St., Sacramento

Florida

3090 S. Monroe St., Tallahassee
13300 E. Colonial Dr., Orlando
2201 Edgewater Dr., Orlando

Georgia

439 Highland Blvd., Atlanta

Illinois

8639 S. Cicero Ave., Chicago
401 W. Armitage Ave., Chicago
2000 Skokie Valley Rd., Highland Park

Iowa

2420 Lincoln Way, Ames
215 Euclid Ave., Des Moines

Massachusetts

55 Summer St., Boston

Michigan

28774 Gratiot Ave., Roseville
27700 Harper Ave., St. Clair Shores

Missouri

2435 Independence Ave., Kansas City
9433 Manchester Rd., Saint Louis
4531 Troost Ave., Kansas City

New York

955 Payne Ave., North Tonawanda
153 Central Ave., Albany
1026 Madison Ave., Albany
1241 Lexington Ave., New York
1654 Richmond Ave., Staten Island

North Carolina

201 W. 4th St., Winston-Salem

Ohio

10825 Kinsman Rd., Cleveland

Pennsylvania

125 E. Main St., Plymouth

Virginia

10390 Willard Way, Fairfax

Washington, D.C.

1117 10th St. NW
1100 4th St. SW
400 Massachusetts Ave. NW
1515 New York Ave. NE (Target location)
4500 Wisconsin Ave. NW (Target location)
7828 Georgia Ave. NW (Target location)

The CVS announced in 2021 that it was going to begin a process of changing its store formats to “drive higher engagement with consumers.” That restructuring effort dubbed “omnichannel health strategy” saw the development of three different store models to serve as community health destinations.

Over three years, between 2022 and 2024, it closed 900 stores and opened 100.

Despite the comany’s realignment process the CVS spokesperson said that “85% of people in the U.S. will still live within 10 miles of a CVS Pharmacy.”